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CAS 88495 63 0 99% Artesunate Artesunatum Antimalarial Agent Water Soluble

CAS 88495 63 0 99% Artesunate Artesunatum Antimalarial Agent Water Soluble

    • CAS 88495 63 0 99% Artesunate Artesunatum Antimalarial Agent Water Soluble
  • CAS 88495 63 0 99% Artesunate Artesunatum Antimalarial Agent Water Soluble

    Product Details:

    Place of Origin: China
    Brand Name: IKNOW
    Certification: GMP,SGS,ISO,HALAL,KOSHER
    Model Number: Iknow-98

    Payment & Shipping Terms:

    Minimum Order Quantity: Negotiable
    Price: Negotiable
    Packaging Details: 25 Kg/Drum 1 Kg/Foil bag
    Delivery Time: 2-5 working days
    Payment Terms: T/T, Western Union, MoneyGram
    Supply Ability: 500 Kg/Per month
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    Detailed Product Description
    Name: Artesunate CAS: 88495 63 0
    Assay: 99% Appearance: White Crystalline Powder, Odorless, Almost Tasteless
    Type: Herbal Extract Botanical Source: Asteraceae Artemisia Annua L.
    Extraction Type: Solvent Extraction Part Of Plant Used: Aboveground
    Melting Point: 133℃
    High Light:

    standardized herbal extracts

    ,

    pure herbal extracts

    CAS 88495 63 0 99% Artesunate Artesunatum Antimalarial Agent Water Soluble

     

    Product Information

     

    According to pharmacological study, Artemisunate has a direct kill effect on plasmodium at erythrocytic stage, but invalid at organizational stage. Clinical research shows that Artemisunate has none of toxic and side effects in clinical treatment of tertian malaria, even the time of malignant protozoon turn to negative is faster than aralen, especially superior for the treatment of malignant malaria and cerebral malaria in anti-aralen-protozoon–strains area.

     

    Product name: Artesunate

    Synonym: Artesunatum

    Chemical name:

    (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl- 3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-ol,hydrogen succinate;

    CAS NO.:88495-63-0

    M.S.:
    CAS 88495 63 0 99% Artesunate Artesunatum Antimalarial Agent Water Soluble 0
    M.F. &M. W. : C19H28O8; 384.43

    Plants source: composites Artemisia annua L. leaf.

    Physical Property: appearance: white crystal. Melting point:129~140℃, odorless, bitter taste. Solubility: freely soluble in chloroform, soluble in acetone, slightly soluble in methanol or ethanol, practically insoluble in water.

    CAS 88495 63 0 99% Artesunate Artesunatum Antimalarial Agent Water Soluble 1

     

    Specification ​

     

    Item

    Specification

    Test Results

    Test Method

    Appearance

    White crystalline powder,

    odorless, almost tasteless

    Complies

    Visual

    Identification

    A ,IR

    B , TLC

    C ,Chemical reaction

    D ,Chemical reaction

    Positive

    Positive

    Complies

    Complies

    IR

    TLC

    Visual

    Visual

    Particle Size

    95% pass through 80 mesh

    Complies

    US Screen

    Melting point

    132 ℃ ~ 135℃

    133℃

    Melting pointApparatus

    Optical rotation

    +2.5 ° ~ +3.5 °

    +3.4°

    Polarimeter

    pH (1%Suspension)

    3.5 ~4.5

    4.3

    pH meter

    Chloride

    ≤0.02%

    <0.02%

    CP2010

    Related substances

    -0.5% ≤impurities ≤1.0%

    No most than one

    One

    HPLC

    -Total impurities

    ≤2.0%

    0.59%

    HPLC

    Heavy metals

    ≤20ppm

    <20ppm

    Visual Colorimetry

    Sulphated Ash

    ≤0.1%

    0.05%

    CP2010

    Loss on drying

    ≤0.5%

    0.15%

    CP2010

    Assay by HPLC

    98.0% ~102.0%

    99.21%

    HPLC

    Conclusion:The above materials conform with IP

     

     

    Function

     

    1) Artesunate is an antimalarial agent. It is a water-soluble hemisuccinate derivative of dihydroartemisinin.
    2) Artemisinin is a sesquiterpene lactone isolated from Artemisia annua, a herb that has traditionally been used in China for the treatment of malaria.
    3) Artesunate and its active metabolite dihydroartemisinin are potent blood schizonticides, active against the ring stage of the parasite.
    4) Artesunate is ideal for the treatment of severe malaria, including cerebral malaria. It is also active against chloroquine and mefloquine resistant strains of P. falciparum.

     

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    6) Samples Small quantity are avaliale at any time

    Contact Details
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